The majority of ties will take place on Tuesday and Wednesday in that week but whoever Chelsea and Fulham draw are likely to play on the Thursday due to their Premier League fixture on the Monday night.
That is also set to create a major knock-on effect, specifically for EFL sides, with their league games then expected to be moved from the Saturday to the Sunday.
There is also a full set of fixtures the following midweek with another enforced change therefore expected as their two opponents will have to play on the Wednesday or have two fixtures in the space of 48 hours.